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HighlightsLamotrigineLamotrigine is used in combination with other anti-seizure drugs in the treatment of some types of seizures. It also is used alone for treating partial seizures in patients 16 years and older when converting from the anti-epileptic drug valproate. Lamotrigine is an oral drug that is used for treating seizures. It is chemically unrelated to other anti-seizure drugs. The precise mechanism by which lamotrigine exerts its anti-seizure action is not known. Lamotrigine can interact with valproic acid. When lamotrigine is begun in patients already receiving valproic acid, the blood concentrations of valproic acid can decrease over a 3-week period.
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