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Promethazine
Promethazine is used to prevent motion sickness, nausea or vomiting, itching associated with allergies or for sedation.Promethazine is a phenothiazine in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine); however, unlike the other drugs in this class, promethazine is not used clinically as an anti-psychotic. It acts as an anti-histamine, a sedative, and an anti-emetic (anti-nausea). Promethazine is used principally as an anti-emetic, to prevent motion sickness or as an anti-histamine in combination with other medications in cough and cold preparations.

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